L-lysine

Structural formula

• Numbering system
• Physical property data
• Toxicological data
• Ecological data
• Molecular structure data
• Computing chemical data
• More
  • Properties and Stability
  • Storage method
  • Synthesis method
  • Purpose

Numbering system

CAS number:56-87-1

MDL number:MFCD00064433

EINECS number:200-294-2

RTECS number:OL5540000

BRN number:1722531

PubChem number:24896404

Physical property data

1. Properties: Colorless needle-like crystals or crystalline powder. Optically active.

2. Density (g/mL, 25/4℃): 1.125

3. Relative vapor density (g/mL, air=1): Undetermined

4. Melting point (ºC): It turns black when heated to 210℃ and decomposes at 224.5℃.

5. Boiling point (ºC, normal pressure): Undetermined

6. Boiling point (ºC, 5.2kPa): Undetermined

7. Refractive index: Undetermined

8. Flash point (ºC): Undetermined

9. Specific rotation (º): α]D20 +14.6° (C=6.5, in water), [ α]D23+25.9° (C=2, in 6mol/L hydrochloric acid)

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure ( kPa, 25ºC): Undetermined

12. Saturated vapor pressure (kPa, 60ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Oil-water (octanol/water) partition coefficient pair Value: Undetermined

17. Explosion upper limit (%, V/V): Undetermined

18. Explosion lower limit (%, V/V): Undetermined

19. Solubility: hygroscopic. Very soluble in water, slightly soluble in ethanol, almost insoluble in ether.

Toxicological data

1. Reproductive toxicity: Oral TDLo of female rats: 138mg/kg, conception takes 5-15 days; Oral TDLo of female rats: 72450mg/kg, conception takes 10-20 days; Oral TDLo of female rats: 90450mg/kg, Conception occurs after 10-20 days; oral TDLo for female rats: 81 mg/kg, conception occurs after 10-20 days; intraperitoneal TDLo for female rats: 44 mg/kg, conception occurs after 5-15 days 2. Mutagenicity: sister chromatid exchangeTEST system : Human lymphocytes: <SPAN lang=E BODY

Ecological data

None yet

Molecular structure data

1. Molar refractive index: 38.43

2. Molar volume (cm³/mol): 129.9

3. Isotonic specific volume (90.2K ): 348.1

4. Surface tension (dyne/cm): 51.5

5. Polarizability (10-24cm3): 15.23

Compute chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 3

3. Number of hydrogen bond acceptors: 4

4. Number of rotatable chemical bonds: 5

5. Number of tautomers: none

6. Topological molecule polar surface area 89.3

7. Number of heavy atoms: 10

8. Surface charge: 0

9. Complexity: 106

10. Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 1

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Properties and stability

1. Found in tobacco leaves.

Storage method

This product should be sealed and stored dry and below 0℃.

Synthesis method

1. L-lysine is generally supplied to the market as L-lysine hydrochloride [657-27-2]. Free L-lysine is easily deliquescent and prone to yellowing and deterioration due to its free amino groups. , and has a pungent fishy smell, making it difficult to store for a long time. L-lysine hydrochloride is relatively stable, not easy to deliquesce, and easy to store. However, the demand for L-lysine in some uses is also increasing, such as peptide synthesis chemistry, biochemical research, and preparation of lysine derivatives. Free L-lysine can be prepared from L-lysine hydrochloride.

2. Tobacco: BU, 22; FC, 21; can be obtained by hydrolysis and refining of animal protein. It can also be synthesized from benzoyl piperidine.

Purpose

For biochemical research. Medium preparation.

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